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In the Abdulghani 1998 head-to-head trial, copper peptide outperformed both vitamin C and tretinoin for procollagen synthesis (70% vs

Those facts were confirmed in animal models of IGF-I deficiency as they often exhibit increased ROS production and decreased NO bioavailability, mimicking the vascular aging phenotype[294]

The trial did have a conflict of interest in that it received support from a company that provides Setria, but it was also a randomized, double-blinded, and placebo-controlled trial with sound methods

Recommended testing schedule: Baseline: Before starting CJC-1295 6 weeks: Assess initial response 12 weeks: Confirm levels before continuing Target: IGF-1 in the upper third of the age-adjusted reference range